Skeletal muscle atrophy in congestive heart failure

It is a paradox: Patients with advanced congestive heart failure lose skeletal muscle mass, but their heart muscles become enlarged to provide the body with an adequate supply of blood and thus with oxygen. It has long been known that the protein angiotensin II plays a villainous role in this process, but the exact mechanism has remained unclear. Now, after seven years of fitting the pieces of this puzzle together, the biologist Dr. Philipp Du Bois and the cardiologist PD Dr. Jens Fielitz of the...